The emulsion used in the PK Oral CBD study was a proprietary micelle nanoencapsulation technology developed by the team at Realize ™. A representation of the micelle structure is shown in Figure 3c for the emulsion delivery system. Micelles containing CBD are able to directly penetrate the UWL and absorb in the GIT. Figure 3c illustrates the micelle penetration of the UWL and absorption into the GIT for the emulsion delivery system.
In the PK Oral CBD study, an emulsion delivery system was used to increase the oral bioavailability of CBD. This delivery system increased the bioavailability of CBD 100x compared to CBD without a delivery system and 25x compared to CBD in a lipid delivery system.
Author: Michael Heller PhD
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